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GPC continued
GPC has other benefits to the healthy human that extend beyond the brain. It serves as an important osmotic buffer, protecting against homeostatic imbalances in the liver, kidneys, and mother's milk as well as in the brain. Being water-soluble and stable in the aqueous phase, GPC is also an important phospholipid reservoir for all the organs. Its ready availability facilitates the production of new cell membrane mass, as required for tissue repair following damage as well as for normal growth and maintenance.
The many clinical trials conducted with GPC prove it is safe to take and well tolerated. Its status as an orthomolecule, present in all the body's cells makes adverse interactions with drugs highly unlikely. Unlike most phospholipid preparations, GPC has a pleasant taste and is stable in water. With its extremely high bioavailability this product is ideally suited for drink formulations.
GlyceroPhosphoCholine (GPC) is a nutrient pro-phospholipid offering impressive benefits for overall mental performance, for brain recovery following damage, and for overall homeostatic support of phospholipid metabolism and cell membrane function. GPC is a highly bioavailable, rapidly absorbed precursor to the membrane phospholipid PC and the essential nutrient choline, as well as a direct metabolic source of the key transmitter acetylcholine. GPC is unique for its capacity to improve baseline attention and recall performance in young, healthy subjects; among middle-aged and elderly subjects its brain benefits are also marked. Its water-compatibility suits it admirably for liquid dosage forms; for specific formulation suggestions using this exciting pro-phospholipid, contact us.
Terminology and Nomenclature We understand that the Merck Index is a kind of “Bible” of the industry for verifying the names of chemicals. However there is a higher power than Merck, and that is the IUPAC (International Union of Pure and Applied Chemistry). IUPAC together with the IUB (International Union of Biochemistry) have a joint IUPAC-IUB Commission on Nomenclature. This is a kind of United Nations of organic chemists, entrusted by consensus to develop appropriate and consistent naming systems for all chemical classes and individual substances. Nevertheless, there is great confusion about the chemical name of GPC. In the NLM/PubMed syetem of peer-reviewed literature we found 8 different descriptions and the frequency of their uses for the same substance:
The recommended name used by the IUPAC-IUB is:
glycero(3)phosphocholine as the correct chemical substance name. GlyceroPhosphoCholine can be used as the preferred substance name, or for short GPC
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|
Glycero(3)phosphocholine |
1871 |
|
GPC |
1499 |
|
Glycerophosphocholine |
999 |
|
Glycerylphosphorylcholine |
667 |
|
L-alpha-glycerylphosphorylcholine |
600 |
|
Choline alfoscerate |
598 |
|
Choline alphoscerate |
598 |
|
sn-glycero(3)phosphocholine |
47 |